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Jinming Li, Yedong Pan, Fanying Guo. Lancet Oncol.. 2025 Aug;26(8):1055-1066
The increasing incidence of early-onset colorectal cancer (age <50 years; EOCRC) shows a dramatic growing trend globally, while late-onset colorectal cancer (LOCRC) is gradually decreasing. Between Jan 1 and Dec 31, 2024, 17 133 tumor samples from patients with colorectal cancer in eight countries were analyzed. In ... Read More
24 Mar, 2026
Thejus Jayakrishnan, Kimmie Ng. JAMA. 2025 Oct 21;334(15):1373-1385
Early-onset gastrointestinal (GI) cancer is typically defined as GI cancer diagnosed in individuals younger than 50 years. The incidence of early-onset GI cancer is rising globally, and early-onset GI cancers represent the most rapidly increasing early-onset cancer in the US. Worldwide, among early-onset GI cancers rep... Read More
24 Mar, 2026
Jian Li, Xiaohong Kuang. Public Health 237 (2024) 336–343
This study aimed to assess the disease burden of cancer in young adults globally and the changes between 2012 and 2022. In young adults, 47.22 % of new cases were breast, thyroid and cervical cancer, while the leading causes of cancer-related death were breast, leukemia and cervical cancer. Compared to 2012, the nu... Read More
24 Mar, 2026
Jiao Su, Yuanhao Liang, Xiaofeng He, et al. Front Nutr. 2024 May 31:11:1384352
Rising trends in early-onset colorectal cancer (CRC) burden have been observed, but the distribution and temporal patterns of early-onset CRC attributable to dietary risks remain unclear. This study aimed to estimate the burden of early-onset CRC attributable to dietary risk factors globally, regionally, and nation... Read More
24 Mar, 2026
Laura Downham, Mathieu Laversanne , Sandra Perdomo, et al JNCI: Journal of the National Cancer Institute, 2025, 00(00), 1–6
Increasing incidence rates of early-onset colorectal cancer (ie, <50years of age) have been reported across multiple countries. We investigated long-term cancer incidence data from 1995 or earlier from Australia, Canada, England, and the United States separately by sex. All countries showed increasing early-onse... Read More
24 Mar, 2026
Hyuna Sung, Rebecca L Siegel, Mathieu Laversanne, et al. Lancet Oncol 2025; 26: 51–63. 2025
Previous studies have shown that colorectal cancer incidence is increasing among younger adults (aged <50 years) in multiple high-income western countries in contrast with stabilizing or decreasing trends in incidence in older adults (aged ≥50 years). In the most recent 5 years (2013–17 for all countries analyse... Read More
24 Mar, 2026
Aaron L. Meyers, James G. Dowty, Khalid Mahmood, et al. The Lancet Regional Health – Western Pacific 2025;64
Early-onset bowel cancer incidence (age <50 years) has increased worldwide. Combining all malignant tumor histologies, early-onset incidence rose 5–9% annually, yielding 4072 excess cases (1⋅5 per 100,000 person-years; 15% appendix, 28% colon, 48% rectum, 9% anus). Trends varied by site, period, and age: appendi... Read More
24 Mar, 2026
Yuzhou Cai, Fangyi Dai, Ying Ye, et al. Sci Rep. 2025 Mar 18;15(1):9347
Breast cancer is the most prevalent malignant disease among women and affects women of reproductive age (15-49 years) across the globe. This study examines patterns and trends in the epidemiology of breast cancer in women of reproductive age using global burden of disease data (1990-2021), with the objective of in... Read More
24 Mar, 2026